Nkhani

MankhwalaMa model amayesa kufotokoza ubale womwe ulipo pakati pa mlingo ndi kuchuluka kwa plasma poyerekeza ndi nthawi. Chitsanzo cha pharmacokinetic ndi chitsanzo cha masamu chomwe chingagwiritsidwe ntchito kulosera kuchuluka kwa mankhwala m'magazi pambuyo pa mlingo wa bolus kapena pambuyo pa kulowetsedwa kwa nthawi yosiyana. Ma model awa nthawi zambiri amachokera mu mawonekedwe oyesa kuchuluka kwa plasma m'mitsempha kapena m'mitsempha pambuyo pa bolus kapena kulowetsedwa m'gulu la odzipereka, pogwiritsa ntchito njira zowerengera zokhazikika komanso ma model a mapulogalamu apakompyuta.

Ma model a masamu amapanga magawo ena a pharmacokinetic monga kuchuluka kwa kugawa ndi kuchotsera. Izi zitha kugwiritsidwa ntchito kuwerengera mlingo wokweza ndi kuchuluka kwa kulowetsedwa kofunikira kuti plasma ikhale yokhazikika pamlingo woyenera.

Popeza zadziwika kuti pharmacokinetics ya mankhwala ambiri oletsa ululu imagwirizana bwino ndi chitsanzo cha magawo atatu, ma algorithms ambiri owunikira kuchuluka kwa magazi ndi malo okhudzidwa afalitsidwa ndipo machitidwe angapo odziyimira pawokha apangidwa.